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Neuregulin 2 antibody (AA 830-855)

NRG2 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031976
$578.58
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  • Target See all Neuregulin 2 (NRG2) Antibodies
    Neuregulin 2 (NRG2)
    Binding Specificity
    • 14
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 830-855
    Reactivity
    • 43
    • 10
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 43
    • 5
    Rabbit
    Clonality
    • 44
    • 4
    Polyclonal
    Conjugate
    • 22
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuregulin 2 antibody is un-conjugated
    Application
    • 26
    • 25
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    Immunohistochemistry (IHC), ELISA
    Cross-Reactivity (Details)
    Expected species reactivity: Rat
    Purification
    Purified
    Immunogen
    A portion of amino acids 830~855 from the human protein was used as the immunogen for this NRG2 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the NRG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the NRG2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Neuregulin 2 (NRG2)
    Alternative Name
    NRG2 (NRG2 Products)
    Synonyms
    NRG2 antibody, Don1 antibody, NTAK antibody, DON1 antibody, HRG2 antibody, NTAK_alpha2a antibody, Ntak antibody, neuregulin 2 antibody, NRG2 antibody, Nrg2 antibody
    Background
    Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.
    UniProt
    O14511
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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