OCT4 antibody (AA 265-297)
Quick Overview for OCT4 antibody (AA 265-297) (ABIN3032294)
Target
See all OCT4 (POU5F1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 265-297
-
Purpose
- Oct3/4 Antibody
-
Purification
- Purified
-
Immunogen
- A portion of amino acids 265-297 from the human protein was used as the immunogen for this Oct3/4 antibody.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- Titration of the Oct3/4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Aliquot the Oct3/4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
-
Alternative Name
- Oct3/4
-
Background
- This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
-
UniProt
- Q01860
-
Pathways
- Stem Cell Maintenance
Target
-