OTX2 antibody (AA 261-289)

Catalog No. ABIN3032101

Product Details anti-OTX2 Antibody

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Binding Specificity: AA 261-289

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): Expected species reactivity: Zebrafish, Xenopus

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 261-289 from the human protein was used as the immunogen for this OTX2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the OTX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the OTX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for OTX2

Target: OTX2 (Orthodenticle Homeobox 2 (OTX2))

Alternative Name: OTX2 (OTX2 Products)

Background: This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.

UniProt: P32243

Pathways: Dopaminergic Neurogenesis