MUC1 antibody (pTyr1229)

Catalog No. ABIN3031863

This anti-MUC1 antibody is a Rabbit Polyclonal antibody detecting MUC1 in ELISA and DB. Suitable for Human.

Quick Overview for MUC1 antibody (pTyr1229) (ABIN3031863)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-MUC1 Antibody

Binding Specificity: pTyr1229

Purification: Antigen affinity purified

Immunogen: This p-MUC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY1229 of human MUC1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the p-MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the p-MUC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: MUC1

Background: MUC1 is a member of the mucin family and a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling