SOX2 antibody (pSer83)
Quick Overview for SOX2 antibody (pSer83) (ABIN3032726)
Target
See all SOX2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer83
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse
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Purification
- Antigen affinity purified
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Immunogen
- This p-SOX2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS83 of human SOX2.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the p-SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the p-SOX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Alternative Name
- SOX2
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Background
- SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
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UniProt
- P48431
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Target
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