Prohibitin antibody (AA 182-211)

Catalog No. ABIN3028945

This Rabbit Polyclonal antibody specifically detects Prohibitin in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Prohibitin antibody (AA 182-211) (ABIN3028945)

Target: Prohibitin (PHB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Prohibitin Antibody

Binding Specificity: AA 182-211

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 182-211 from the human protein was used as the immunogen for this PHB antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PHB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PHB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Prohibitin

Target: Prohibitin (PHB)

Alternative Name: PHB

Background: Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling