Src antibody (pTyr530)

Catalog No. ABIN3029560

This Rabbit Polyclonal antibody specifically detects Src in ELISA, IHC and DB. It exhibits reactivity toward Human.

Quick Overview for Src antibody (pTyr530) (ABIN3029560)

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Src antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Product Details anti-Src Antibody

Binding Specificity: pTyr530

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Chicken, Zebrafish

Purification: Antigen affinity purified

Immunogen: This phospho-Src antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY530 of human Src.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Src

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Alternative Name: Src

Background: This protein has tyrosine kinase activity and belongs to the src family of proteins.

UniProt: P12931

Pathways: JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling