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PITX2 antibody (AA 42-71)
PITX2
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PITX2 Antibody
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Target
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PITX2
(Paired-Like Homeodomain 2 (PITX2))
Binding Specificity
All epitopes for PITX2 antibodies
AA 42-71
Reactivity
All reactivities for PITX2 antibodies
Human
Host
All hosts for PITX2 antibodies
Rabbit
Clonality
All clonalities for PITX2 antibodies
Polyclonal
Conjugate
All conjugates for PITX2 antibodies
This PITX2 antibody is un-conjugated
Application
All applications for PITX2 antibodies
Western Blotting (WB), ELISA
Purification
Antigen affinity purified
Immunogen
A portion of amino acids 42-71 from the human protein was used as the immunogen for this PITX2 antibody.
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Titration of the PITX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the PITX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for PITX2
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Target
PITX2
(Paired-Like Homeodomain 2 (PITX2))
Alternative Name
PITX2 (PITX2 Products )
Synonyms
ARP1 antibody, Brx1 antibody, IDG2 antibody, IGDS antibody, IGDS2 antibody, IHG2 antibody, IRID2 antibody, Otlx2 antibody, PTX2 antibody, RGS antibody, RIEG antibody, RIEG1 antibody, RS antibody, 9430085M16Rik antibody, Brx1a antibody, Brx1b antibody, Munc30 antibody, Pitx2a antibody, Pitx2b antibody, Pitx2c antibody, Pitx2cbeta antibody, Ptx2 antibody, Rieg antibody, pitx2a antibody, pitx2c antibody, zgc:110508 antibody, XPtx2b antibody, xPtx2 antibody, xpitx2 antibody, arp1 antibody, brx1 antibody, idg2 antibody, igds antibody, igds2 antibody, ihg2 antibody, irid2 antibody, otlx2 antibody, pitx2-A antibody, ptx2 antibody, rgs antibody, rieg antibody, rieg1 antibody, pitx-2 antibody, pitx2 antibody, paired like homeodomain 2 antibody, paired-like homeodomain transcription factor 2 antibody, paired-like homeodomain 2 antibody, paired like homeodomain 2 S homeolog antibody, paired like homeodomain 2 L homeolog antibody, PITX2 antibody, Pitx2 antibody, pitx2 antibody, pitx2.S antibody, pitx2.L antibody
Background
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
UniProt
Q99697
Pathways
Retinoic Acid Receptor Signaling Pathway , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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