OCT4 antibody (N-Term)
Quick Overview for OCT4 antibody (N-Term) (ABIN3032292)
Target
See all OCT4 (POU5F1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 128-161, N-Term
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Purpose
- Pou5f1 Antibody
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Purification
- Antigen affinity
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Immunogen
- This Pou5f1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 128-161 amino acids from the N-terminal region of zebrafish Pou5f1.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the Pou5f1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Pou5f1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Alternative Name
- Pou5f1
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Background
- Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t- POU2 causes developmental retardation or arrest before gastrulation.
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UniProt
- Q90270
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Pathways
- Stem Cell Maintenance
Target
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