PRMT3 antibody (AA 142-173)

Catalog No. ABIN3032358

Product Details anti-PRMT3 Antibody

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Binding Specificity: AA 142-173

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Purified

Immunogen: A portion of amino acids 142-173 from the human protein was used as the immunogen for this PRMT3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PRMT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-2000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PRMT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PRMT3

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Alternative Name: PRMT3 (PRMT3 Products)

Synonyms: HRMT1L3 antibody, 2010005E20Rik antibody, 2410018A17Rik antibody, AL033309 antibody, Hrmt1l3 antibody, PRMT3 antibody, hrmt1l3 antibody, zgc:112498 antibody, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 3 antibody, ATPRMT3 antibody, protein arginine methyltransferase 3 antibody, protein arginine methyltransferase 3 antibody, protein arginine N-methyltransferase 3 antibody, protein arginine methyltransferase 3 S homeolog antibody, PRMT3 antibody, Prmt3 antibody, prmt3 antibody, prmt3.S antibody

Background: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

UniProt: O60678

Pathways: Protein targeting to Nucleus