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PRMT5 antibody (AA 473-499)

This anti-PRMT5 antibody is a Rabbit Polyclonal antibody detecting PRMT5 in WB and ELISA. Suitable for Human.
Catalog No. ABIN3032361

Quick Overview for PRMT5 antibody (AA 473-499) (ABIN3032361)

Target

See all PRMT5 Antibodies
PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Reactivity

  • 92
  • 41
  • 23
  • 8
  • 6
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
Human

Host

  • 83
  • 6
  • 2
  • 1
Rabbit

Clonality

  • 70
  • 21
  • 1
Polyclonal

Conjugate

  • 55
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PRMT5 antibody is un-conjugated

Application

  • 61
  • 33
  • 32
  • 15
  • 14
  • 14
  • 13
  • 9
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 15
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 473-499

    Cross-Reactivity (Details)

    Expected species reactivity: Mouse, Bovine, Primate, Xenopus

    Purification

    Purified

    Immunogen

    A portion of amino acids 473-499 from the human protein was used as the immunogen for this PRMT5 antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the PRMT5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the PRMT5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

    Alternative Name

    PRMT5

    Background

    Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

    UniProt

    O14744

    Pathways

    Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
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