Prohibitin antibody (AA 92-121)

Catalog No. ABIN3032314

This Rabbit Polyclonal antibody specifically detects Prohibitin in WB, IHC, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for Prohibitin antibody (AA 92-121) (ABIN3032314)

Target: Prohibitin (PHB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-Prohibitin Antibody

Binding Specificity: AA 92-121

Cross-Reactivity (Details): Expected species reactivity: Bovine, Chicken

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 92-121 from the human protein was used as the immunogen for this Prohibitin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Prohibitin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Prohibitin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Prohibitin

Target: Prohibitin (PHB)

Alternative Name: Prohibitin

Background: Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling