RAD51C antibody (AA 169-198)

Catalog No. ABIN3032429

The Rabbit Polyclonal anti-RAD51C antibody has been validated for WB and ELISA. It is suitable to detect RAD51C in samples from Human.

Quick Overview for RAD51C antibody (AA 169-198) (ABIN3032429)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD51C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAD51C Antibody

Binding Specificity: AA 169-198

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 169-198 from the human protein was used as the immunogen for this RAD51C antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the RAD51C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the RAD51C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Alternative Name: RAD51C

Background: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

UniProt: O43502

Pathways: DNA Damage Repair