Rhodopsin antibody (AA 310-339)

Catalog No. ABIN3032473

This Rabbit Polyclonal antibody specifically detects Rhodopsin in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Rhodopsin antibody (AA 310-339) (ABIN3032473)

Target: Rhodopsin (RHO)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rhodopsin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Rhodopsin Antibody

Binding Specificity: AA 310-339

Cross-Reactivity (Details): Expected species reactivity: Primate

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the RHO antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the RHO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Rhodopsin

Target: Rhodopsin (RHO)

Alternative Name: rho (Rhodopsin)

Target Type: Chemical

Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.

UniProt: P08100

Pathways: WNT Signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction