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Sonic Hedgehog antibody (AA 395-450)

SHH Reactivity: Human, Mouse WB, ELISA, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029025
  • Target See all Sonic Hedgehog (SHH) Antibodies
    Sonic Hedgehog (SHH)
    Binding Specificity
    • 15
    • 11
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 395-450
    Reactivity
    • 60
    • 53
    • 40
    • 17
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 72
    • 10
    • 8
    • 1
    • 1
    Rabbit
    Clonality
    • 65
    • 27
    Polyclonal
    Conjugate
    • 52
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sonic Hedgehog antibody is un-conjugated
    Application
    • 72
    • 31
    • 25
    • 14
    • 13
    • 11
    • 10
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 395-450 were used as immunogen for this Shh antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SHH Primary Antibody
  • Application Notes
    Titration of the Shh antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The 45 kDa precursor protein autocleaves into 27 kDa amino and 19 kDa carboxy fragments.\. Flow Cytometry: 1:25,Western blot: 1:1000 (1)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Shh antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Sonic Hedgehog (SHH)
    Alternative Name
    Shh (SHH Products)
    Synonyms
    HHG1 antibody, HLP3 antibody, HPE3 antibody, MCOPCB5 antibody, SMMCI antibody, TPT antibody, TPTPS antibody, 9530036O11Rik antibody, Dsh antibody, Hhg1 antibody, Hx antibody, Hxl3 antibody, M100081 antibody, fc83d08 antibody, shh antibody, syu antibody, vhh-1 antibody, vhh1 antibody, wu:fc83d08 antibody, Xhh antibody, hedgehog antibody, xshh antibody, SHH antibody, twh antibody, twhh antibody, sonic hedgehog antibody, sonic hedgehog a antibody, sonic hedgehog L homeolog antibody, sonic hedgehog protein A antibody, sonic hedgehog b antibody, SHH antibody, Shh antibody, shha antibody, shh.L antibody, shh antibody, shhb antibody
    Background
    Sonic hedgehog binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO.
    UniProt
    Q62226
    Pathways
    Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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