SIRT3 antibody (AA 250-279)

Catalog No. ABIN3032590

This Rabbit Polyclonal antibody specifically detects SIRT3 in WB, IHC and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for SIRT3 antibody (AA 250-279) (ABIN3032590)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SIRT3 Antibody

Binding Specificity: AA 250-279

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 250-279 from the human protein was used as the immunogen for this SIRT3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SIRT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3

Background: SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.

UniProt: Q9NTG7