Expected species reactivity: Bovine, Chicken, Mouse, Zebrafish
Purification
Antigen affinity purified
Immunogen
This SMAD1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 297-330 amino acids from the Central region of human SMAD1.
Titration of the SMAD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the SMAD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
SMAD1
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
Alternative Name
SMAD1
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.