SMC2 antibody (AA 1166-1197)

Catalog No. ABIN3029033

Product Details anti-SMC2 Antibody

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Binding Specificity: AA 1166-1197

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: A portion of amino acids 1166-1197 from the human protein was used as the immunogen for this SMC2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SMC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SMC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Alternative Name: SMC2 (SMC2 Products)

Synonyms: CAP-E antibody, CAPE antibody, SMC-2 antibody, SMC2L1 antibody, 5730502P04Rik antibody, AI255214 antibody, AW545314 antibody, Fin16 antibody, Smc2l1 antibody, fb92e05 antibody, wu:fb92e05 antibody, zeh1628 antibody, zgc:55326 antibody, xcap-e antibody, SCII antibody, structural maintenance of chromosomes 2 antibody, structural maintenance of chromosomes 2 L homeolog antibody, SMC2 antibody, Smc2 antibody, smc2 antibody, smc2.L antibody

Background: SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

UniProt: O95347