SSB antibody (AA 66-96)

Catalog No. ABIN3032748

Product Details anti-SSB Antibody

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Binding Specificity: AA 66-96

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSB antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Purified

Immunogen: A portion of amino acids 66-96 from the human protein was used as the immunogen for this SSB antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SSB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SSB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SSB

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Alternative Name: SSB (SSB Products)

Synonyms: LARP3 antibody, La antibody, lab1 antibody, larp3 antibody, ssb antibody, Mt-SSB antibody, MtSSB antibody, Ssbp1 antibody, SS-B antibody, laa-a antibody, ssb-a antibody, ssb-b antibody, wu:fb17f11 antibody, zgc:55588 antibody, Sjogren syndrome antigen B antibody, Sjogren syndrome antigen B L homeolog antibody, single stranded DNA binding protein 1 antibody, Sjogren syndrome antigen B S homeolog antibody, Sjogren syndrome antigen B (autoantigen La) antibody, SSB antibody, ssb.L antibody, SSBP1 antibody, Ssb antibody, ssb.S antibody, ssb antibody

Background: SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. This protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.

UniProt: P05455