LKB1 antibody (AA 387-417)

Catalog No. ABIN3029003

The Rabbit Polyclonal anti-LKB1 antibody has been validated for ELISA and IHC. It is suitable to detect LKB1 in samples from Human.

Quick Overview for LKB1 antibody (AA 387-417) (ABIN3029003)

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LKB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-LKB1 Antibody

Binding Specificity: AA 387-417

Purification: Purified

Immunogen: A portion of amino acids 387-417 from the human protein was used as the immunogen for this STK11 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the STK11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the STK11 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for LKB1

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Alternative Name: STK11 (LKB1)

Background: STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

UniProt: Q15831

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect