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SUMO2 antibody

SUMO2 Reactivity: Human, Rat WB, ELISA, IF Host: Mouse Monoclonal 973CT8-1-1 unconjugated
Catalog No. ABIN3032647
  • Target See all SUMO2 Antibodies
    SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
    Reactivity
    • 109
    • 34
    • 29
    • 8
    • 2
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 94
    • 23
    • 1
    Mouse
    Clonality
    • 96
    • 23
    Monoclonal
    Conjugate
    • 59
    • 13
    • 10
    • 9
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SUMO2 antibody is un-conjugated
    Application
    • 79
    • 69
    • 47
    • 20
    • 15
    • 9
    • 9
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Expected species reactivity: Bovine, Chicken, Hamster, Mouse, Pig, Primate
    Purification
    Purified
    Immunogen
    Purified His-tagged protein was used to produced this monoclonal SUMO-2 antibody.
    Clone
    973CT8-1-1
    Isotype
    IgG2b
    Top Product
    Discover our top product SUMO2 Primary Antibody
  • Application Notes
    Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the SUMO-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))
    Alternative Name
    SUMO-2 (SUMO2 Products)
    Background
    Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
    UniProt
    P61956
    Pathways
    Methionine Biosynthetic Process
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