SYK antibody (AA 195-223)
Quick Overview for SYK antibody (AA 195-223) (ABIN3032716)
Target
See all SYK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 195-223
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Cross-Reactivity (Details)
- Expected species reactivity: Chicken, Rat
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 195-223 from the mouse protein was used as the immunogen for this Syk antibody.
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Isotype
- Ig Fraction
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anti-Spleen tyrosine Kinase (SYK) (AA 5-360) antibody
SYK Reactivity: Human, Mouse, Rat WB, IP, IHC (p), ICC Host: Mouse Monoclonal SYK-01 unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525) antibodySYK Reactivity: Human, Mouse, Rat, Monkey WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr348) antibodySYK Reactivity: Human, Mouse, Rat, Monkey WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibodySYK Reactivity: Human, Mouse, Rat, Monkey WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (Internal Region) antibodySYK Reactivity: Human, Mouse, Rat WB, IF, IP, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reactivity: Human ELISA, ICC, FACS Host: Mouse Monoclonal 2G11E6 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 3D1G10 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 387-417), (C-Term) antibodySYK Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB03097 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 374-635) antibodySYK Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525), (pTyr526) antibodySYK Reactivity: Human, Mouse WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
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Application Notes
- Titration of the Syk antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Syk antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SYK (Spleen tyrosine Kinase (SYK))
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Alternative Name
- Syk
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Background
- Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).
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UniProt
- P48025
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Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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