TBP antibody

Catalog No. ABIN3029100

This anti-TBP antibody is a Mouse Monoclonal antibody detecting TBP in WB, ELISA and IHC (p). Suitable for Human, Mouse, Rat and Monkey.

Quick Overview for TBP antibody (ABIN3029100)

Target: TBP (TATA Box Binding Protein (TBP))

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 830CT4-3-3

Product Details anti-TBP Antibody

Purification: Purified

Immunogen: Purified His-tagged protein was used to produced this monoclonal TBP antibody.

Isotype: IgG1

Application Details

Application Notes: Titration of the TBP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Western blot: 1:1000-2:000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TBP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TBP

Target: TBP (TATA Box Binding Protein (TBP))

Alternative Name: TBP

Background: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

UniProt: P20226

Pathways: WNT Signaling