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TSG101 antibody (AA 340-370)
TSG101
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TSG101 Antibody
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Target
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TSG101
(Tumor Susceptibility Gene 101 (TSG101))
Binding Specificity
All epitopes for TSG101 antibodies
AA 340-370
Reactivity
All reactivities for TSG101 antibodies
Human
Host
All hosts for TSG101 antibodies
Rabbit
Clonality
All clonalities for TSG101 antibodies
Polyclonal
Conjugate
All conjugates for TSG101 antibodies
This TSG101 antibody is un-conjugated
Application
All applications for TSG101 antibodies
Western Blotting (WB), ELISA
Cross-Reactivity (Details)
Expected species reactivity: Mouse, Rat
Purification
Purified
Immunogen
A portion of amino acids 340-370 from the human protein was used as the immunogen for this TSG101 antibody.
Isotype
Ig Fraction
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Discover our top product TSG101 Primary Antibody
Alternatives
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Application Details
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Application Notes
Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the TSG101 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for TSG101
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Target
TSG101
(Tumor Susceptibility Gene 101 (TSG101))
Alternative Name
TSG101 (TSG101 Products )
Synonyms
CG9712 antibody, DmTSG101 antibody, Dmel\\CG9712 antibody, ESCRT-I antibody, Tsg101 antibody, burs antibody, dTSg101 antibody, dTsg101 antibody, dVps23 antibody, ept antibody, tsg101 antibody, vps23 antibody, TSG101 antibody, MGC76193 antibody, TSG10 antibody, VPS23 antibody, AI255943 antibody, CC2 antibody, Rw antibody, zgc:86926 antibody, tumor susceptibility 101 antibody, Tumor susceptibility gene 101 antibody, Tumor Susceptibility Gene homolog antibody, tumor susceptibility gene 101 antibody, tumor susceptibility 101a antibody, tumor susceptibility 101 L homeolog antibody, TSG101 antibody, tsg-101 antibody, tsg101 antibody, Tsg101 antibody, tsg101a antibody, tsg101.L antibody
Background
TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
UniProt
Q99816
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