VANGL2 antibody (AA 37-65)
Quick Overview for VANGL2 antibody (AA 37-65) (ABIN3029570)
Target
See all VANGL2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 37-65
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Cross-Reactivity (Details)
- Expected species reactivity: Rat
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 37-65 from the human protein was used as the immunogen for this VANGL2 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the VANGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the VANGL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- VANGL2 (Vang-Like 2 (VANGL2))
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Alternative Name
- VANGL2
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Background
- Planar cell polarity (PCP) is the term given to global cell polarization, such as the alignment of mammalian body hair along the anterior-posterior axis or the orientation of steriocilia bundles in the inner ear. VANGL2 is a PCP protein that is involved in the transmission of directional cues to align either individual cells within an epithelial sheet or multicellular clusters, which polarize as a group.
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UniProt
- Q9ULK5
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Pathways
- WNT Signaling, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization
Target
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