VEGFA antibody (AA 66-95)

Catalog No. ABIN3029576

The Rabbit Polyclonal anti-VEGFA antibody has been validated for WB and ELISA. It is suitable to detect VEGFA in samples from Human.

Quick Overview for VEGFA antibody (AA 66-95) (ABIN3029576)

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VEGFA Antibody

Binding Specificity: AA 66-95

Purification: Purified

Immunogen: A portion of amino acids 66-95 from the human protein was used as the immunogen for this VEGFA antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the VEGFA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the VEGFA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for VEGFA

Target: VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

Alternative Name: VEGFA

Background: VEGFA is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGFA have been associated with proliferative and nonproliferative diabetic retinopathy.

UniProt: P15692

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling