ZEB2 antibody (AA 1078-1105)

Catalog No. ABIN3029671

Product Details anti-ZEB2 Antibody

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Binding Specificity: AA 1078-1105

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZEB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1078-1105 from the human protein was used as the immunogen for this ZEB2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ZEB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ZEB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Alternative Name: ZEB2 (ZEB2 Products)

Synonyms: ZFHX1B antibody, Zfhx1b antibody, HSPC082 antibody, SIP-1 antibody, SIP1 antibody, SMADIP1 antibody, 9130203F04Rik antibody, D130016B08Rik antibody, Zfx1b antibody, Zfxh1b antibody, mKIAA0569 antibody, XSip1 antibody, sip1 antibody, zfhx1b antibody, si:dkey-52o2.2 antibody, sip1a antibody, wu:fc92g08 antibody, sip1b antibody, zinc finger E-box binding homeobox 2 antibody, zinc finger E-box binding homeobox 2 S homeolog antibody, zinc finger homeobox protein antibody, zinc finger E-box binding homeobox 2a antibody, zinc finger E-box binding homeobox 2b antibody, ZEB2 antibody, Zeb2 antibody, zeb2.S antibody, zeb2 antibody, zeb2a antibody, zeb2b antibody

Background: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.

UniProt: O60315

Pathways: Tube Formation