TJP1 antibody (C-Term)

Catalog No. ABIN3029132

The Rabbit Polyclonal anti-TJP1 antibody has been validated for WB and ELISA. It is suitable to detect TJP1 in samples from Human.

Quick Overview for TJP1 antibody (C-Term) (ABIN3029132)

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TJP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TJP1 Antibody

Binding Specificity: C-Term

Purification: Antigen affinity purified

Immunogen: This ZO1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1328-1362 amino acids from the C-terminal region of human TJP1/ZO1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ZO1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ZO1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TJP1

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Alternative Name: ZO1

Background: The N-terminal of ZO1 may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.

UniProt: Q07157

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization