RORC antibody

Catalog No. ABIN4966337

The Rabbit Polyclonal anti-RORC antibody is suitable to detect RORC in samples from Arabidopsis thaliana and Zea mays. It has been validated for WB.

Quick Overview for RORC antibody (ABIN4966337)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivity: Arabidopsis thaliana, Zea mays

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RORC Antibody

Purpose: Anti-TOR | Target of rapamycin

Cross-Reactivity (Details): Arabidopsis thaliana, Zea mays
Not reactive in: Chlamydomonas reinhardtii

Predicted Reactivity: Cucumis sativus,Glycne max,Nicotiana tabacum,Oryza sativa,Phaseolus vulgaris,Physcomitrium patens,Populus trichocarpa,Setaria italica,Setaria viridis,Solanum tuberosum,Sorghum bicolor,Vitis vinifera

Purification: Immunogen affinity purified serum

Immunogen: KLH-conjugated synthetic peptide derived from Arabidopsis thaliana TOR protein sequence

Application Details

Application Notes: 1 : 5000 (WB)

Comment:

TOR is a subjected to post-translational modifications (ubiquitination and phosphorylation), which can change the migration pattern in SDS gel.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μL of sterile water

Buffer: Immunogen affinity purified serum in PBS pH 7.4.

Handling Advice: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Storage: -20 °C

Storage Comment: Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Target Details for RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Alternative Name: Target of rapamycin (TOR)

Background: TOR (Target of rapamycin) is an essential cell growth regulator that controls development from early embryo to seed production in response to nutrient availability in envoronmental stress conditions. It belongs to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR is expressed in embryos, endosperm and meristems. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.

Molecular Weight: 279 kDa

Gene ID: 841427

UniProt: Q9FR53

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway