Catalase antibody

Catalog No. ABIN498107

The Rabbit Polyclonal anti-Catalase antibody is suitable to detect Catalase in samples from Human, Mouse and Rat. It has been validated for IHC (p).

Quick Overview for Catalase antibody (ABIN498107)

Target: Catalase (CAT)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Catalase antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Catalase Antibody

Specificity: This antibody antibody detects endogenous levels of Catalase protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: Immunohistochemistry: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Catalase

Target: Catalase (CAT)

Alternative Name: Catalase

Background: Catalase is a peroxisome specific marker protein belonging to the catalase family. Defects in the gene encoding for the catalase protein, CAT, can cause acatalasi,a a disease characterized by the absence of catalase activity in red cells and associated with ulcerating oral lesions. Catalase is also an important regulator of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis. Catalase, which can form a homotetramer, is found in nearly all aerobically respiring organisms and functions in protecting cells from the toxic effects of hydrogen peroxide.Synonyms: CAT, Peroxisome Marker

Gene ID: 847

NCBI Accession: NP_001743

UniProt: P04040

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism