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Ephrin B1 antibody
EFNB1
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Ephrin B1 Antibody
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Target
See all Ephrin B1 (EFNB1) Antibodies
Ephrin B1 (EFNB1)
Reactivity
All reactivities for Ephrin B1 antibodies
Human, Mouse, Rat
Host
All hosts for Ephrin B1 antibodies
Rabbit
Clonality
All clonalities for Ephrin B1 antibodies
Polyclonal
Conjugate
All conjugates for Ephrin B1 antibodies
This Ephrin B1 antibody is un-conjugated
Application
All applications for Ephrin B1 antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous levels of Ephrin-B1 protein.
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity
> 95 % (by SDS-PAGE)
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Alternatives
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Application Details
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Application Notes
Western blot: 1: 500 - 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for Ephrin B1
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Target
Ephrin B1 (EFNB1)
Alternative Name
Ephrin-B1 (EFNB1 Products )
Synonyms
EFNB1 antibody, LERK2 antibody, Cek5-L antibody, EFL-3 antibody, Elk-L antibody, Epl2 antibody, Eplg2 antibody, LERK-2 antibody, Lerk2 antibody, Stra1 antibody, CFND antibody, CFNS antibody, EFL3 antibody, EPLG2 antibody, cfnd antibody, cfns antibody, efl3 antibody, efnb1-A antibody, ephrinB1 antibody, eplg2 antibody, lerk2 antibody, ephrin B1 antibody, ephrin-B1 antibody, ephrin-B1 L homeolog antibody, EFNB1 antibody, Efnb1 antibody, efnb1 antibody, efnb1.L antibody
Background
Ephrins are the ligands which bind to the Eph receptor subfamily, the largest group of the receptor tyrosine kinase family. Both ephrins and Eph receptors are broadly expressed through the ectoderm, mesoderm, and endoderm of vertebrate embryos. Two classes of ephrins exist: Class A ephrins are tethered to the membrane by a GPI linkage and bind primarily to EphA receptors, Class B ephrins contain a membrane-spanning region and bind predominantly to EphB receptors. Ephrin B1 may play a role in constraining the orientation of longitudinally projecting axons.Synonyms: CEK5 LIgand, CEK5-L, EFL-3, EFL3, EFNB1, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPLG2, LERK-2, LERK2
Molecular Weight
approx. 38 kDa
Gene ID
1947
NCBI Accession
NP_004420
UniProt
P98172
Pathways
RTK Signaling
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