NFYC antibody
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- Target See all NFYC Antibodies
- NFYC (Nuclear Transcription Factor Y, gamma (NFYC))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NFYC antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of NF-YC protein. (region surrounding Trp85)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product NFYC Primary Antibody
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- Application Notes
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- NFYC (Nuclear Transcription Factor Y, gamma (NFYC))
- Alternative Name
- NFYC (NFYC Products)
- Synonyms
- CBF-C antibody, CBFC antibody, H1TF2A antibody, HAP5 antibody, HSM antibody, NF-YC antibody, fb98f01 antibody, wu:fb98f01 antibody, zgc:55514 antibody, cbf-c antibody, cbfc antibody, h1tf2a antibody, hap5 antibody, hsm antibody, nf-yc antibody, NFYC antibody, Nfyc antibody, nuclear transcription factor Y subunit gamma antibody, nuclear transcription factor Y, gamma antibody, nuclear transcription factor Y subunit gamma L homeolog antibody, nuclear transcription factor-Y gamma antibody, nuclear Y/CCAAT-box binding factor C subunit NF-YC antibody, NFYC antibody, nfyc antibody, nfyc.L antibody, Nfyc antibody
- Background
- The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein histone-fold Synonyms: Nuclear transcription factor Y subunit gamma, Transactivator HSM-1/2
- Molecular Weight
- approx. 50 kDa
- Gene ID
- 4802
- NCBI Accession
- NP_055038
- UniProt
- Q13952
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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