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Cnpase antibody
CNP
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Cnpase Antibody
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Target
See all Cnpase (CNP) Antibodies
Cnpase (CNP)
(2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))
Reactivity
All reactivities for Cnpase antibodies
Human, Mouse, Rat
Host
All hosts for Cnpase antibodies
Rabbit
Clonality
All clonalities for Cnpase antibodies
Polyclonal
Conjugate
All conjugates for Cnpase antibodies
This Cnpase antibody is un-conjugated
Application
All applications for Cnpase antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects endogenous levels of CNPase protein. (region surrounding Ala108)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography
Purity
> 95 % by SDS-PAGE
Top Product
Discover our top product CNP Primary Antibody
Alternatives
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anti-2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) (AA 151-250) antibody
CNP
Reactivity: Human, Mouse, Rat
WB, ELISA, FACS, IHC (p), IF (cc), ICC, IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Cnpase
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Target
Cnpase (CNP)
(2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))
Alternative Name
CNPase (CNP Products )
Synonyms
CNP1 antibody, CNPase antibody, Cnp-1 antibody, Cnp1 antibody, CNPF antibody, CNPI antibody, CNPII antibody, CNP antibody, DKFZp469F1421 antibody, cnpl antibody, fd21d08 antibody, fi37a10 antibody, rich antibody, sb:cb662 antibody, si:ch73-158e11.4 antibody, wu:fd21d08 antibody, wu:fd44a05 antibody, wu:fi35d08 antibody, wu:fi37a10 antibody, cnp antibody, 2',3'-cyclic nucleotide 3' phosphodiesterase antibody, CNP antibody, Cnp antibody, cnp antibody, cnp.L antibody
Background
CNPase (2',3'-Cyclic Nucleotide 3'-Phosphodiesterase) exists in two forms: 46 kDa (CNP1) and 48 kDa (CNP2). It is expressed at high levels by oligodendrocytes in the central nervous system and by Schwann cells in the peripheral nervous system and is virtual absent in other cell types. CNPase activity is decreased in demyelinating diseases such as multiple sclerosis. CNPase gene is localized to chromosome 17q21, very near the BRCA 1 familial breast cancer gene.Synonyms: 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNP1, Oligodendrocyte Marker
Molecular Weight
approx. 48 kDa
Gene ID
1267
NCBI Accession
NP_149124
UniProt
P09543
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