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Cholecystokinin antibody

CCK Reactivity: Human, Rat, Mouse IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN498541
  • Target See all Cholecystokinin (CCK) Antibodies
    Cholecystokinin (CCK)
    Reactivity
    • 28
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 30
    • 5
    Rabbit
    Clonality
    • 30
    • 5
    Polyclonal
    Conjugate
    • 20
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cholecystokinin antibody is un-conjugated
    Application
    • 15
    • 15
    • 14
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of CCK protein. (region surrounding Val46)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product CCK Primary Antibody
  • Application Notes
    Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Cholecystokinin (CCK)
    Alternative Name
    Cholecystokinin / CCK (CCK Products)
    Synonyms
    CCK antibody, CCK-CH antibody, cck-a antibody, cck-b antibody, cholecystokinin antibody, cholecystokinin L homeolog antibody, CCK antibody, Cck antibody, cck antibody, cck.L antibody
    Background
    CCK (cholecystokinin) is a 115 amino acid secreted protein belonging to the gastrin/cholecystokinin family. CCK has been shown to stimulate the growth of pancreatic cancer. As a peptide hormone, CCK induces gallbladder contraction and the release of pancreatic enzymes in the gut. Binding of CCK to CCK-A receptors stimulates amylase release from the pancreas, while binding to CCK-B receptors stimulates gastric acid secretion. The function of CCK in the brain is not clear. The CCK precursor is cleaved by proteases to produce a number of active cholecystokinins including CCK58, CCK58 desnonopeptide, CCK39, CCK33, CCK25, CCK18, CCK12, CCK8, CCK7 and CCK5.
    Molecular Weight
    approx. 13 kDa
    Gene ID
    885
    NCBI Accession
    NP_000720
    UniProt
    P06307
    Pathways
    TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Feeding Behaviour
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