CD55 antibody

Catalog No. ABIN499054

This Rabbit Polyclonal antibody specifically detects CD55 in WB. It exhibits reactivity toward Human.

Quick Overview for CD55 antibody (ABIN499054)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD55 Antibody

Specificity: This antibody detects endogenous levels of CD55 protein. (region surrounding Lys142)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55 / DAF

Background: Avoidance by host tissues of attack by autologous complement proteins is dependent in part on the activities of membrane regulatory factors. One molecule involved in this control is a 70 kD glycoprotein termed decay-accelerating factor (DAF), or CD55. Interruption by CD55 of the complement sequence at an early step in activation effectively halts progression of the cascade and prevents consequent cell injury. In man, CD55 is expressed on the plasma membrane of all cell types that are in intimate contact with plasma complement proteins.Synonyms: Complement decay-accelerating factor

Molecular Weight: approx. 41 kDa

Gene ID: 1604

NCBI Accession: NP_000565

UniProt: P08174

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity