MGST1 antibody

Catalog No. ABIN499090

Product Details anti-MGST1 Antibody

Target: MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGST1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of MGST1 protein. (region surrounding Arg74)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for MGST1

Target: MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

Alternative Name: MGST1 (MGST1 Products)

Synonyms: gst12 antibody, mgst antibody, mgst-i antibody, zgc:101898 antibody, MGST1 antibody, GST12 antibody, MGST antibody, MGST-I antibody, 1500002K10Rik antibody, Gst antibody, microsomal glutathione S-transferase 1 L homeolog antibody, microsomal glutathione S-transferase 1.1 antibody, microsomal glutathione S-transferase 1 pseudogene antibody, microsomal glutathione S-transferase 1 antibody, mgst1.L antibody, mgst1.1 antibody, LOC473380 antibody, MGST1 antibody, mgst1 antibody, CpipJ_CPIJ015233 antibody, CpipJ_CPIJ018241 antibody, Mgst1 antibody

Background: Microsomal glutathione transferase 1 (MGST1) is an abundant protein that catalyzes the conjugation of electrophilic compounds with glutathione, as well as the reduction of lipid hydroperoxides. The level of MGST1 mRNA in rat are highest in liver, while the levels of expression vary in non-hepatic tissues. In addition, the subcellular localization patterns of MGST1 are highly tissue specific. In hepatocytes and bile ducts, MGST1 is localized to the cytoplasm. MGST1 is localized to the nucleus in choroid plexus and primary spermatocytes and displays a granular cytoplasmic staining pattern in the adrenal medulla). Also, focal staining of MGST1 is observed in the distal tubules and collecting ducts of the liver.Synonyms: GST12, MGST, Microsomal GST-1, Microsomal glutathione S-transferase 1

Molecular Weight: approx. 18 kDa

Gene ID: 4257

NCBI Accession: NP_064696

UniProt: P10620