MGST1 antibody
Quick Overview for MGST1 antibody (ABIN499090)
Target
See all MGST1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody detects endogenous levels of MGST1 protein. (region surrounding Arg74)
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography using epitope-specific immunogen
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Purity
- > 95 % pure by SDS-PAGE
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Application Notes
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))
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Alternative Name
- MGST1
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Background
- Microsomal glutathione transferase 1 (MGST1) is an abundant protein that catalyzes the conjugation of electrophilic compounds with glutathione, as well as the reduction of lipid hydroperoxides. The level of MGST1 mRNA in rat are highest in liver, while the levels of expression vary in non-hepatic tissues. In addition, the subcellular localization patterns of MGST1 are highly tissue specific. In hepatocytes and bile ducts, MGST1 is localized to the cytoplasm. MGST1 is localized to the nucleus in choroid plexus and primary spermatocytes and displays a granular cytoplasmic staining pattern in the adrenal medulla). Also, focal staining of MGST1 is observed in the distal tubules and collecting ducts of the liver.Synonyms: GST12, MGST, Microsomal GST-1, Microsomal glutathione S-transferase 1
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Molecular Weight
- approx. 18 kDa
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Gene ID
- 4257
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NCBI Accession
- NP_064696
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UniProt
- P10620
Target
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