CREB3L1 antibody (C-Term)

Catalog No. ABIN499118

The Goat Polyclonal anti-CREB3L1 antibody is suitable to detect CREB3L1 in samples from Human, Mouse and Rat. It has been validated for WB and EIA.

Quick Overview for CREB3L1 antibody (C-Term) (ABIN499118)

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This CREB3L1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CREB3L1 Antibody

Binding Specificity: C-Term

Sequence: C-DFSHSKEWFH DRD

Specificity: This antibody recognizes OASIS / CREB3L1

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_443086.1.

Application Details

Application Notes: Peptide ELISA: Detection Limit: 1/32000. Western blot: 1-3 μg/mL. Approx 60 kDa band observed in lysates of cell line A549(calculated MW of 57.0 kDa according to NP_443086.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Alternative Name: CREB3L1 / OASIS

Background: OASIS is a putative CREB/ATF family transcription factor with a putative C-terminal hydrophobic transmembrane domain. It can activate transcription through box-B elements but not through CRE of somatostatin. Shortening of the OASIS transmembrane domain results in a significant increase in transcriptional activity and changes its subcellular localization from the endoplasmic reticulum to the nucleus. The CREB3L1 gene encodes a protein with a transmembrane domain that is a transcriptional activator of the CREB/ATF family.Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 1, Old astrocyte specifically-induced, PSEC0238, cAMP-responsive element-binding protein 3-like protein 1

Gene ID: 90993

NCBI Accession: NP_443086

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding