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CDIP1 antibody (Center)

CDIP1 Reactivity: Human, Mouse WB, IF, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499607
  • Target See all CDIP1 Antibodies
    CDIP1 (LITAF-Like Protein (CDIP1))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 6
    • 4
    • 1
    Human, Mouse
    Host
    • 5
    • 2
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 7
    This CDIP1 antibody is un-conjugated
    Application
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to CDIP.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    19 amino acid peptide near the center of Human CDIP
    Isotype
    IgG
    Top Product
    Discover our top product CDIP1 Primary Antibody
  • Application Notes
    ELISA. Western Blot: CDIP antibody can be used for detection of CDIP at 0.25 - 0.5 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CDIP1 (LITAF-Like Protein (CDIP1))
    Alternative Name
    LITAF-Like Protein (CDIP1 Products)
    Synonyms
    RGD1310686 antibody, MGC165666 antibody, MGC97537 antibody, 2700048O17Rik antibody, 5730403B10Rik antibody, AU018521 antibody, AW742692 antibody, CDIP antibody, C16orf5 antibody, I1 antibody, LITAFL antibody, MGC52765 antibody, MGC127651 antibody, cell death-inducing p53 target 1 antibody, LITAF-like protein antibody, cell death inducing Trp53 target 1 antibody, cell death inducing p53 target 1 antibody, cell death-inducing p53 target 1 L homeolog antibody, Cdip1 antibody, cdip1 antibody, Bm1_00175 antibody, LOC100168843 antibody, CDIP1 antibody, cdip1.L antibody
    Background
    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death, loss of its functions contributes to the development of most cancers. CDIP is a novel pro-apoptotic target gene whose inhibition abrogates p53-mediated apoptotic responses. Overexpression of CDIP induced apoptosis in transfected cells while siRNA suppression of caspase-8 mRNA blocked this CDIP-induced apoptosis, indicating that the CDIP-dependent apoptosis pathway proceeds through extrinsic cell death pathway. CDIP may thus represent a novel target for drug design to maximize p53 response and sensitize tumor cells to cancer therapy. Multiple isoforms of CDIP are known to exist.Synonyms: C16orf5, CDIP, Cell death-inducing protein, Transmembrane protein I1
    Gene ID
    29965
    NCBI Accession
    NP_037531
    UniProt
    Q9H305
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