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CIDEB antibody (C-Term)

This anti-CIDEB antibody is a Rabbit Polyclonal antibody detecting CIDEB in WB and EIA. Suitable for Mouse.
Catalog No. ABIN499629

Quick Overview for CIDEB antibody (C-Term) (ABIN499629)

Target

See all CIDEB Antibodies
CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reactivity

  • 23
  • 12
  • 4
  • 3
Mouse

Host

  • 23
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Rabbit

Clonality

  • 23
  • 3
Polyclonal

Conjugate

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  • 1
  • 1
This CIDEB antibody is un-conjugated

Application

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  • 7
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Binding Specificity

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    • 2
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    • 2
    • 1
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    C-Term

    Specificity

    CIDE-B antibody was raised against a peptide corresponding to amino acids 204 to 219 of murine CIDE-B. It has no cross activity to CIDE-A.

    Purification

    Affinity chromatography purified via peptide column

    Immunogen

    Mouse mCIDE-B (C-Terminus) Peptide

    Isotype

    IgG
  • Application Notes

    ELISA. Western Blot: CIDE-B antibody can be used for detection of CIDE-B at 1/500 to 1/1000dilution. An approximately 25 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C.
  • Target

    CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

    Alternative Name

    CIDE-B

    Background

    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (1).CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow (1).Synonyms: CIDE B, CIDEB, Cell Death Activator CIDE-B, Cell Death-Inducing DFFA-Like Effector B

    Gene ID

    12684

    UniProt

    O70303
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