AMPD3 antibody (AbBy Fluor® 750)

Catalog No. ABIN4996427

This anti-AMPD3 antibody is a Rabbit Polyclonal antibody detecting AMPD3 in WB and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for AMPD3 antibody (AbBy Fluor® 750) (ABIN4996427)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMPD3 antibody is conjugated to AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-AMPD3 Antibody (AbBy Fluor® 750)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AMPD3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Alternative Name: AMPD3

Background:

Synonyms: Adenosine monophosphate deaminase isoform E, Adenosine monophosphate deaminase 3, AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, Ampd3, AMPD3_HUMAN, Erythrocyte AMP deaminase, Erythrocyte specic AMP deaminase, Erythrocyte type AMP deaminase, Myoadenylate deaminase.

Background: AMP deaminase plays a critical role in energy metabolism.Involvement in diseaseDefects in AMPD3 are the cause of adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE), also known as erythrocyte AMP deaminase deficiency. AMPDDE is a metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase. It is a clinically asymptomatic condition characterized by a 50 % increase in steady-state levels of ATP in affected cells. Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders.

Gene ID: 272