AMPD3 antibody (AA 280-360)

Catalog No. ABIN7221116

This Rabbit Polyclonal antibody specifically detects AMPD3 in IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AMPD3 antibody (AA 280-360) (ABIN7221116)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMPD3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-AMPD3 Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-AMPD3 Polyclonal Antibody

Specificity: AMPD3 Polyclonal Antibody detects endogenous levels of AMPD3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human AMPD3 at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Alternative Name: AMPD3

Background: AMPD3, AMP deaminase 3, AMP deaminase isoform E, Erythrocyte AMP deaminaseAMPD3 encodes a member of the AMP deaminase gene family. The adenosine monophosphate deaminase 3 is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Gene ID: 272

UniProt: Q01432