BACE2 antibody (AA 101-200) (AbBy Fluor® 750)
Quick Overview for BACE2 antibody (AA 101-200) (AbBy Fluor® 750) (ABIN4997144)
Target
See all BACE2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 101-200
-
Cross-Reactivity
- Rat
-
Predicted Reactivity
- Human,Mouse,Dog,Cow,Sheep,Pig
-
Purification
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human BACE2
-
Isotype
- IgG
-
-
-
-
Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Expiry Date
- 12 months
-
-
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
-
Alternative Name
- BACE2
-
Background
-
Synonyms: ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1, Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Asp 1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, BACE2, UNQ418/PRO852
Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
-
Gene ID
- 25825
-
UniProt
- Q9Y5Z0
Target
-