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BACE2 antibody (AA 101-200) (AbBy Fluor® 750)

This anti-BACE2 antibody is a Rabbit Polyclonal antibody detecting BACE2 in IF (cc) and IF (p). Suitable for Rat.
Catalog No. ABIN4997144

Quick Overview for BACE2 antibody (AA 101-200) (AbBy Fluor® 750) (ABIN4997144)

Target

See all BACE2 Antibodies
BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Reactivity

  • 48
  • 35
  • 13
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Rat

Host

  • 69
  • 3
  • 1
Rabbit

Clonality

  • 71
  • 2
Polyclonal

Conjugate

  • 35
  • 12
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BACE2 antibody is conjugated to AbBy Fluor® 750

Application

  • 55
  • 30
  • 28
  • 12
  • 12
  • 12
  • 11
  • 8
  • 8
  • 4
  • 3
  • 3
  • 3
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 14
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    Cross-Reactivity

    Rat

    Predicted Reactivity

    Human,Mouse,Dog,Cow,Sheep,Pig

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human BACE2

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

    Alternative Name

    BACE2

    Background

    Synonyms: ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1, Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Asp 1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, BACE2, UNQ418/PRO852

    Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

    Gene ID

    25825

    UniProt

    Q9Y5Z0
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