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FAIM antibody (C-Term)

FAIM Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499820
  • Target See all FAIM Antibodies
    FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))
    Binding Specificity
    • 15
    • 9
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 46
    • 18
    • 15
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 59
    • 2
    Rabbit
    Clonality
    • 61
    Polyclonal
    Conjugate
    • 20
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAIM antibody is un-conjugated
    Application
    • 29
    • 26
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to FAIM.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    FAIM antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human FAIM.
    Isotype
    IgG
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    Discover our top product FAIM Primary Antibody
  • Application Notes
    ELISA. Western Blot: 5 - 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))
    Alternative Name
    FAIM (FAIM Products)
    Synonyms
    FAIM1 antibody, FAIM antibody, faim antibody, zgc:92712 antibody, zgc:92723 antibody, Fas apoptotic inhibitory molecule antibody, Fas apoptotic inhibitory molecule L homeolog antibody, Fas apoptotic inhibitory molecule b antibody, Fas apoptotic inhibitory molecule a antibody, FAIM antibody, Faim antibody, faim antibody, faim.L antibody, Tsp_00038 antibody, faimb antibody, faima antibody
    Background
    The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite outgrowth in different neuronal systems by a mechanism involving the activation of NF-kappaB and the Ras-ERK pathway.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1
    Gene ID
    55179
    NCBI Accession
    NP_060617
    UniProt
    Q9NVQ4
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