GOLM1 antibody (Center)
Quick Overview for GOLM1 antibody (Center) (ABIN499902)
Target
See all GOLM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Center
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- GOLPH2 antibody was raised against an 18 amino acid peptide from near the center of human GOLPH2.
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Isotype
- IgG
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Application Notes
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ELISA. Western Blot: 0.25 - 0.5 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- GOLM1 (Golgi Membrane Protein 1 (GOLM1))
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Alternative Name
- Golgi Membrane Protein 1 / GOLM1
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Background
- GOLPH2, also known as GOLM1, is a Golgi phosphoprotein that has a short cytoplasmic N-terminal domain, a membrane spanning region, and a longer C-terminal domain. It was initially identified as a possible marker for Alzheimer's disease, although later studies have demonstrated that the GOLPH2 gene does not contribute to risk of this disease. GOLPH2 expression has been reported higher in prostate cancer tissues compared to normal prostate tissue, suggesting that GOLPH2 can be used as an additional positive marker for tissue-based diagnosis of prostate cancer. It has been suggested that GOLPH2 expression in hepatocellular carcinomas (HCCs) and serum may also serve as tumor markers for HCCs.Synonyms: C9orf155, GOLPH2, Golgi marker, Golgi membrane protein GP73, Golgi phosphoprotein 2, PSEC0242
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Gene ID
- 51280
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NCBI Accession
- NP_057632
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UniProt
- Q8NBJ4
Target
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