CHPF antibody (AA 51-150) (Biotin)

Catalog No. ABIN5000017

The Rabbit Polyclonal anti-CHPF antibody has been validated for WB, IHC (p) and IHC (fro). It is suitable to detect CHPF in samples from Human.

Quick Overview for CHPF antibody (AA 51-150) (Biotin) (ABIN5000017)

Target: CHPF (Chondroitin Polymerizing Factor (CHPF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHPF antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CHPF Antibody (Biotin)

Binding Specificity: AA 51-150

Specificity: May have slight cross reactivity with CHPF2 due to sequence similarity of the following amino acids "RTRYI" within the immunogen

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHPF

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CHPF

Target: CHPF (Chondroitin Polymerizing Factor (CHPF))

Alternative Name: CHPF

Background:

Synonyms: Chondroitin sulfate synthase 2, Chondroitin-polymerizing factor, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II, N-acetylgalactosaminyltransferase 2

Background: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress.

Gene ID: 79586

UniProt: Q8IZ52

Pathways: Glycosaminoglycan Metabolic Process, SARS-CoV-2 Protein Interactome