Cytokeratin 18 antibody (pSer52) (AbBy Fluor® 680)
Quick Overview for Cytokeratin 18 antibody (pSer52) (AbBy Fluor® 680) (ABIN5000088)
Target
See all Cytokeratin 18 (KRT18) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer52
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Cross-Reactivity
- Mouse
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Predicted Reactivity
- Rat
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from mouse CK18 around the phosphorylation site of Ser52 [SR(p-S)VW]
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Isotype
- IgG
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Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Alternative Name
- CK18
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Background
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Synonyms: Keratin, type I cytoskeletal 18, Cytokeratin endo B, Keratin D, Cytokeratin-18, CK-18, Keratin-18, K18, Krt18, Kerd, Krt1-18
Background: When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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Gene ID
- 16668
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Pathways
- Apoptosis, Caspase Cascade in Apoptosis
Target
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