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Cytokeratin 18 antibody (pSer52) (AbBy Fluor® 680)

This Rabbit Polyclonal antibody specifically detects Cytokeratin 18 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.
Catalog No. ABIN5000088

Quick Overview for Cytokeratin 18 antibody (pSer52) (AbBy Fluor® 680) (ABIN5000088)

Target

See all Cytokeratin 18 (KRT18) Antibodies
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity

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  • 18
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  • 1
Mouse

Host

  • 191
  • 179
  • 3
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  • 1
Rabbit

Clonality

  • 228
  • 145
  • 3
Polyclonal

Conjugate

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This Cytokeratin 18 antibody is conjugated to AbBy Fluor® 680

Application

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    pSer52

    Cross-Reactivity

    Mouse

    Predicted Reactivity

    Rat

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from mouse CK18 around the phosphorylation site of Ser52 [SR(p-S)VW]

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Alternative Name

    CK18

    Background

    Synonyms: Keratin, type I cytoskeletal 18, Cytokeratin endo B, Keratin D, Cytokeratin-18, CK-18, Keratin-18, K18, Krt18, Kerd, Krt1-18

    Background: When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

    Gene ID

    16668

    Pathways

    Apoptosis, Caspase Cascade in Apoptosis
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