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Cytokeratin 18 antibody (AA 53-150) (AbBy Fluor® 680)

This anti-Cytokeratin 18 antibody is a Rabbit Polyclonal antibody detecting Cytokeratin 18 in WB, FACS, IF (cc) and IF (p). Suitable for Human, Mouse, Rat and Pig.
Catalog No. ABIN5000090

Quick Overview for Cytokeratin 18 antibody (AA 53-150) (AbBy Fluor® 680) (ABIN5000090)

Target

See all Cytokeratin 18 (KRT18) Antibodies
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity

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Human, Mouse, Rat, Pig

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Cytokeratin 18 antibody is conjugated to AbBy Fluor® 680

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    AA 53-150

    Cross-Reactivity

    Human, Mouse, Pig, Rat

    Predicted Reactivity

    Dog,Cow,Horse,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CK18

    Isotype

    IgG
  • Application Notes

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Alternative Name

    CK18

    Background

    Synonyms: K18, CYK18, Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, KRT18, PIG46

    Background: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

    Gene ID

    3875

    UniProt

    P05783

    Pathways

    Apoptosis, Caspase Cascade in Apoptosis
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