CRTAM antibody (AA 31-130) (AbBy Fluor® 680)

Catalog No. ABIN5000576

The AbBy Fluor® 680-conjugated Rabbit Polyclonal anti-CRTAM antibody (ABIN5000576) specifically detects CRTAM in FACS, IF (cc) and IF (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for CRTAM antibody (AA 31-130) (AbBy Fluor® 680) (ABIN5000576)

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTAM antibody is conjugated to AbBy Fluor® 680

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CRTAM Antibody (AbBy Fluor® 680)

Binding Specificity: AA 31-130

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRTAM

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CRTAM

Background:

Synonyms: CD355, Cytotoxic and regulatory T-cell molecule, Class-I MHC-restricted T-cell-associated molecule, CRTAM

Background: Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Gene ID: 56253

UniProt: O95727

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation