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NKIRAS2 antibody (C-Term)

NKIRAS2 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500114
  • Target See all NKIRAS2 Antibodies
    NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))
    Binding Specificity
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 38
    • 14
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 36
    • 2
    Rabbit
    Clonality
    • 36
    • 2
    Polyclonal
    Conjugate
    • 17
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NKIRAS2 antibody is un-conjugated
    Application
    • 26
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is specific for kappaB-ras2 and has no cross-reactivity to kappaB-ras1.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    KappaB ras2 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human KappaB ras2.
    Isotype
    IgG
    Top Product
    Discover our top product NKIRAS2 Primary Antibody
  • Application Notes
    ELISA. Western blot: 0.5 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))
    Alternative Name
    NKIRAS2 (NKIRAS2 Products)
    Synonyms
    NKIRAS2 antibody, KBRAS2 antibody, kappaB-Ras2 antibody, zgc:92870 antibody, 2410003M04Rik antibody, 4930527H08Rik antibody, D630018G21Rik antibody, NFKB inhibitor interacting Ras like 2 antibody, NFKB inhibitor interacting Ras-like 2 antibody, NFKB inhibitor interacting Ras like 2 L homeolog antibody, NFKB inhibitor interacting Ras-like protein 2 antibody, NKIRAS2 antibody, Nkiras2 antibody, nkiras2 antibody, nkiras2.L antibody
    Background
    KappaB ras-1 (kappaB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkappaB), an inhibitor of the transcription factor NF-kappaB. IkappaB exists in two homologous forms, IkappaB-alpha and IkappaB-beta, although IkappaB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkappaB-alpha-NF-kappaB complexes can shuttle in and out of the nucleus, IkappaB-beta-NF-kappaB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkappaB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkappaB-beta and regulating the rate of degradation of IkappaB-beta.Synonyms: KBRAS2, NF-kappa-B inhibitor-interacting Ras-like protein 2
    Gene ID
    28511
    NCBI Accession
    NP_060065
    UniProt
    Q9NYR9
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