DKK3 antibody (AA 31-130) (AbBy Fluor® 680)

Catalog No. ABIN5001290

The AbBy Fluor® 680-conjugated Rabbit Polyclonal anti-DKK3 antibody (ABIN5001290) specifically detects DKK3 in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for DKK3 antibody (AA 31-130) (AbBy Fluor® 680) (ABIN5001290)

Target: DKK3

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKK3 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DKK3 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 31-130

Purpose: DKK3 Polyclonal Antibody, AbBy Fluor-680 Conjugated

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DKK3

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DKK3

Target: DKK3

Background:

Synonyms: RIG, REIC, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, UNQ258/PRO295

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Gene ID: 27122

UniProt: Q9UBP4